It depends on the type of character. Like, with the mage, I use the space bar for med and target next. So, every time I hit the spacebar a different enemy target will appear and then I can use a repeater macro or a spell cast that will target current.
In most of the initial attacks, you want to create a line depending on that character type but I think the main thing is going to be to go into war mode, then target nearest, this way you can click inside the target gump. Plus, if everybody gets near the same target they can use the macro to attack that target.
But you could add things to it after that. So, you would go war mode, target nearest, attack current, all kill, target current and then perhaps, Honor could be added in the beginning and if you're using a weapon, concecrate weapon and divine fury and then your weapon special. So, that would all be in the same initial attack line and happen in about 2 seconds depending on spell times.
Like, with a Sampire, you might build a string of commands to attack nearest target, whirl wind, repeat a few times, add in concecrate weapon and divine fury when those timers run out and then repeat. So, you can kind of put it on cruise control.
With a Bard, you're going to want an enemy list or attackable list so that when the spawn pops up you click on the bar, that puts it into the target gump, then click your peace repeater or discord and then just make sure you have target current. Same with provo. Just make a macro to target current, provo, target next, use target.
And I use timings after alot of the string is finished. Like, with lightning strike off the initial attack but usually by that time I have used a different macro but if I haven't, it will just keep lightning striking about 8 or 9 times.
And I use target self on the side of the mouse. There's a whole lot of ways to target and you have to be careful not to use attack target in some cases because you will attack EVs or people but you might want to create different situations and build the macros for those situations depending on if there are EVs or no EVs, stuff like that.