I would recommend saving paragon chests until you're up to something like 95 skill. Or would it be better to wait until 99.5? Hmm.
(Lockpicking is sadly useless at the lower levels. You can use it to collect wands but that's pretty much it).
Note that the chest is not valuable due to it's contents. The chests come with maps inside, one level higher then what the creature could normally drop; they're the only way to get lvl6 maps (which always lead to a marti), so only those "top level" chests could be considered to hold anything valuable at all.
The other bits of loot consist of a couple of gems, a small amount of gold, and some dodgy magic items. Maybe a wand. The chest itself is more valuable.
That is to say, you're better off asking (perhaps even hiring) another player to open it for you, unless you're seriously considering making a treasure hunting character.