I believe the last patch did something to macros on Gaming Keyboard settings.
1) Last night, 3 of us in GoL had issues with our macros after logging in.
2) We all run on G15 keyboards
3) We cycled through our M1, M2, and M3 keys several times which fixed our macro problems.
To my knowledge, only the 3 of us with G15's were affected and cycling the M keys fixed our macro issues.
Hope this info helpful in some way.