1. Enchant weapon might work without focus/imbuing according to the description in the spellbook. You don't get spell-channelling bonus without focus/imbuing though.
2. Mystic weapon (mastery) might work without focus/imbuing. Having said 1., you can equip a nice spell-channeling bow, cast mystic weapon and enchant it with a hit spell.
Also, If you human, you get the +20 jack of all trades racial bonus for focus, which is enough to get a weak healing stone aka a few free healing pots.