Being only a registry change, I'd say you just have to try that and see - let us know your result;
"The default state (Nagling enabled) improves performance by allowing several small packets to be combined together into a single, larger packet for more efficient transmission. While this improves overall performance and reduces TCP/IP overhead, it may briefly delay transmission of smaller packets. Keep in mind that disabling Nagle's algorithm may have some negative effect on file transfers, and can only help reduce delay in some games"